For individuals living with Parkinson's disease, managing symptoms often involves a careful balance of medications. 

Austedo Parkinson's Medication: Understanding Its Role in Dyskinesia Management

For individuals living with Parkinson's disease, managing symptoms often involves a careful balance of medications. While levodopa remains a cornerstone therapy for many, its long-term use can sometimes lead to a challenging side effect known as dyskinesia. Austedo (deutetrabenazine) is a prescription medication specifically approved to help manage this type of involuntary movement associated with Parkinson's disease.

What is Dyskinesia in Parkinson's Disease?

Dyskinesia refers to uncontrolled, involuntary movements that can manifest as swaying, fidgeting, bobbing, or writhing. These movements are distinct from the tremors and rigidity typically associated with Parkinson's itself. Levodopa-induced dyskinesia often appears after several years of levodopa treatment and can range in severity, impacting a person's ability to perform daily activities and significantly affecting their quality of life.

How Austedo Helps with Parkinson's Dyskinesia

Austedo is a medication designed to reduce the severity and frequency of these involuntary movements. It does not treat the underlying Parkinson's disease itself, nor is it a substitute for levodopa. Instead, it works in conjunction with existing Parkinson's treatments to address a specific motor complication.

Mechanism of Action

Austedo belongs to a class of drugs known as vesicular monoamine transporter 2 (VMAT2) inhibitors. Its mechanism involves regulating the amount of certain neurotransmitters, particularly dopamine, that are released into the brain. In the context of Parkinson's dyskinesia, it is believed that by modulating these neurotransmitter levels, Austedo helps to dampen the overactivity that contributes to the involuntary movements experienced by patients on levodopa therapy.

Important Considerations for Austedo Use

As with any prescription medication, using Austedo requires careful consideration and professional medical guidance. It is crucial for patients and their caregivers to understand the potential benefits and risks.

• Dosage and Administration: Austedo is taken orally, typically twice daily. The dosage is individualized and determined by a healthcare provider based on the patient's specific needs and response to treatment.


• Potential Side Effects: Common side effects can include drowsiness, diarrhea, dry mouth, and fatigue. More serious side effects, though less common, can also occur. It is essential to discuss all potential side effects with your doctor.


• Interactions: Austedo may interact with other medications, including certain antidepressants, antipsychotics, and other drugs that affect heart rhythm. Always provide a complete list of all medications, supplements, and herbal remedies you are taking to your healthcare provider.


• Monitoring: Regular monitoring by your doctor is necessary to assess the medication's effectiveness and to manage any potential side effects. Do not adjust your dosage or stop taking Austedo without consulting your doctor.

Consult Your Healthcare Professional

This article provides general information about Austedo Parkinson's medication and its role in managing dyskinesia. It is not intended to provide medical advice, diagnosis, or treatment. Deciding if Austedo is the right treatment option for you can only be made in consultation with a qualified healthcare professional who can assess your individual health condition, existing medications, and overall treatment plan. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment.